4-溴苯甲酰氯
外觀
4-溴苯甲酰氯 | |
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別名 | 對溴苯甲酰氯 |
識別 | |
CAS號 | 586-75-4 ![]() |
PubChem | 68515 |
性質 | |
化學式 | C7H4BrClO |
摩爾質量 | 219.46 g·mol−1 |
熔點 | 42 °C(315 K) |
沸點 | 246 °C(519 K) |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
4-溴苯甲酰氯是一種有機化合物,化學式為C7H4BrClO,它是苯甲酰氯苯環對位的氫被溴取代的化合物。它可由4-溴苯甲酸和草酰氯在二甲基甲酰胺的催化下於二氯甲烷中反應得到[1],酰氯化試劑也可使用氯化亞碸[2]。它和苯胺在三乙胺的存在下於四氫呋喃中反應,可以得到N-苯基-4-溴苯甲酰胺。[3]
參考文獻
[編輯]- ^ Kay Ahn, Markus Boehm, Matthew F. Brown, Jessica Calloway, Ye Che, Jinshan Chen, Kimberly F. Fennell, Kieran F. Geoghegan, Adam M. Gilbert, Jemy A. Gutierrez, Amit S. Kalgutkar, Adhiraj Lanba, Chris Limberakis, Thomas V. Magee, Inish O』Doherty, Robert Oliver, Brandon Pabst, Jayvardhan Pandit, Kevin Parris, Jeffrey A. Pfefferkorn, Timothy P. Rolph, Rushi Patel, Brandon Schuff, Veerabahu Shanmugasundaram, Jeremy T. Starr, Alison H. Varghese, Nicholas B. Vera, Cecile Vernochet, Jiangli Yan. Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism. ACS Chemical Biology. 2016-09-16, 11 (9): 2529–2540 [2021-09-20]. ISSN 1554-8929. doi:10.1021/acschembio.6b00266 (英語).
- ^ Hugo Gallardo, Rodrigo Cristiano, André Vieira, Ricardo Neves Filho, Rajendra Srivastava. Sonogashira Coupling Applied in the Synthesis of 1,2,4-Oxadiazole-Based Nonsymmetrical Liquid Crystals. Synthesis. 2008-02, 2008 (4): 605–609 [2021-09-20]. ISSN 0039-7881. doi:10.1055/s-2008-1032156. (原始內容存檔於2018-06-03) (英語).
- ^ Clarice A. D. Caiuby, Matheus P. de Jesus, Antonio C. B. Burtoloso. α-Imino Iridium Carbenes from Imidoyl Sulfoxonium Ylides: Application in the One-Step Synthesis of Indoles. The Journal of Organic Chemistry. 2020-06-05, 85 (11): 7433–7445 [2021-09-20]. ISSN 0022-3263. doi:10.1021/acs.joc.0c00833. (原始內容存檔於2021-11-07) (英語).