3-羥基吡啶-2-甲酸
外觀
3-羥基吡啶-2-甲酸 | |
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IUPAC名 3-Hydroxypyridine-2-carboxylic acid | |
別名 | 3-Hydroxypicolinic acid 3-Hydroxy-2-pyridinecarboxylic acid |
識別 | |
CAS號 | 874-24-8 ![]() |
PubChem | 13401 |
ChemSpider | 12827 |
SMILES |
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InChI |
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InChIKey | BRARRAHGNDUELT-UHFFFAOYAC |
ChEBI | 63432 |
性質 | |
化學式 | C6H5NO3 |
摩爾質量 | 139.109 g·mol⁻¹ |
外觀 | 淺黃色針狀晶體 |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
3-羥基吡啶-2-甲酸是一種有機化合物,化學式為C6H5NO3,它可通過3-氨基吡啶-2-甲酸的重氮化反應製得,它在214~215 °C分解。[1]它和金屬鹽反應,可以得到相應的配合物。[2][3]它和甲醇在硫酸存在下回流反應,可以得到3-羥基吡啶-2-甲酸甲酯。[4]
參考文獻
[編輯]- ^ Lewis R. Fibel, Paul E. Spoerri. The Synthesis and Investigation of Pyridine and Pyrazine Analogs of Salicylates 1,2. Journal of the American Chemical Society. 1948-11, 70 (11): 3908–3911 [2022-03-09]. ISSN 0002-7863. doi:10.1021/ja01191a113. (原始內容存檔於2022-03-09) (英語).
- ^ Boris-Marko Kukovec, Pedro D.Vaz, Maria José Calhorda, Zora Popović. Structural preferences and isomerism in nickel(II) and copper(II) complexes with 3-hydroxypicolinic acid. Polyhedron. 2012-05, 39 (1): 66–75 [2022-03-09]. doi:10.1016/j.poly.2012.03.040. (原始內容存檔於2020-02-19) (英語).
- ^ Tanja Koleša-Dobravc, Keiichi Maejima, Yutaka Yoshikawa, Anton Meden, Hiroyuki Yasui, Franc Perdih. Bis(picolinato) complexes of vanadium and zinc as potential antidiabetic agents: synthesis, structural elucidation and in vitro insulin-mimetic activity study. New Journal of Chemistry. 2018, 42 (5): 3619–3632 [2022-03-09]. ISSN 1144-0546. doi:10.1039/C7NJ04189F (英語).
- ^ Tatiana N. Pashirova, Anissa Braïki, Irina V. Zueva, Konstantin A. Petrov, Vasily M. Babaev, Evgenia A. Burilova, Darya A. Samarkina, Ildar Kh. Rizvanov, Eliana B. Souto, Ludovic Jean, Pierre-Yves Renard, Patrick Masson, Lucia Ya. Zakharova, Oleg G. Sinyashin. Combination delivery of two oxime-loaded lipid nanoparticles: Time-dependent additive action for prolonged rat brain protection. Journal of Controlled Release. 2018-11, 290: 102–111 [2022-03-09]. doi:10.1016/j.jconrel.2018.10.010. (原始內容存檔於2021-03-08) (英語).