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4-苄基哌啶

維基百科,自由的百科全書
4-苄基哌啶
法律規範狀態
法律規範
  • The NpSG do not apply to this substance, because it is not a 2-Phenylethylamine derivative
  • PSA
識別資訊
  • 4-(phenylmethyl)piperidine
CAS號31252-42-3  checkY
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.045.926 編輯維基數據鏈接
化學資訊
化學式C12H17N
摩爾質量175.28 g·mol−1
3D模型(JSmol英語JSmol
  • C1CNCCC1CC2=CC=CC=C2
  • InChI=1S/C12H17N/c1-2-4-11(5-3-1)10-12-6-8-13-9-7-12/h1-5,12-13H,6-10H2 checkY
  • Key:ABGXADJDTPFFSZ-UHFFFAOYSA-N checkY

4-苄基哌啶(化學式:C12H17N)是一種單胺釋放劑,釋放多巴胺的選擇性是血清素的20到48倍。它可由哌啶苯甲醛反應,再經催化氫化得到。[1]它和三氟乙酸酐二氯甲烷中反應,可以得到N-三氟甲醯基-4-苄基哌啶。[2]

參考文獻

[編輯]
  1. ^ Zeng Hong, Xin Ge, Shaodong Zhou. Underlying Mechanisms of Reductive Amination on Pd-Catalysts: The Unique Role of Hydroxyl Group in Generating Sterically Hindered Amine. International Journal of Molecular Sciences. 2022-07-10, 23 (14): 7621 [2023-03-07]. ISSN 1422-0067. doi:10.3390/ijms23147621. (原始內容存檔於2022-10-01) (英語). 
  2. ^ Karine Alarcon, Adeline Martz, Laetitia Mony, Jacques Neyton, Pierre Paoletti, Maurice Goeldner, Bernard Foucaud. Reactive derivatives for affinity labeling in the ifenprodil site of NMDA receptors. Bioorganic & Medicinal Chemistry Letters. 2008-05, 18 (9): 2765–2770 [2023-03-07]. doi:10.1016/j.bmcl.2008.04.019. (原始內容存檔於2022-08-02) (英語).