跳转到内容

4-苄基哌啶

维基百科,自由的百科全书
4-苄基哌啶
法律规范状态
法律规范
  • The NpSG do not apply to this substance, because it is not a 2-Phenylethylamine derivative
  • PSA
识别信息
  • 4-(phenylmethyl)piperidine
CAS号31252-42-3  checkY
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.045.926 编辑维基数据链接
化学信息
化学式C12H17N
摩尔质量175.28 g·mol−1
3D模型(JSmol英语JSmol
  • C1CNCCC1CC2=CC=CC=C2
  • InChI=1S/C12H17N/c1-2-4-11(5-3-1)10-12-6-8-13-9-7-12/h1-5,12-13H,6-10H2 checkY
  • Key:ABGXADJDTPFFSZ-UHFFFAOYSA-N checkY

4-苄基哌啶(化学式:C12H17N)是一种单胺释放剂,释放多巴胺的选择性是血清素的20到48倍。它可由哌啶苯甲醛反应,再经催化氢化得到。[1]它和三氟乙酸酐二氯甲烷中反应,可以得到N-三氟甲酰基-4-苄基哌啶。[2]

参考文献

[编辑]
  1. ^ Zeng Hong, Xin Ge, Shaodong Zhou. Underlying Mechanisms of Reductive Amination on Pd-Catalysts: The Unique Role of Hydroxyl Group in Generating Sterically Hindered Amine. International Journal of Molecular Sciences. 2022-07-10, 23 (14): 7621 [2023-03-07]. ISSN 1422-0067. doi:10.3390/ijms23147621. (原始内容存档于2022-10-01) (英语). 
  2. ^ Karine Alarcon, Adeline Martz, Laetitia Mony, Jacques Neyton, Pierre Paoletti, Maurice Goeldner, Bernard Foucaud. Reactive derivatives for affinity labeling in the ifenprodil site of NMDA receptors. Bioorganic & Medicinal Chemistry Letters. 2008-05, 18 (9): 2765–2770 [2023-03-07]. doi:10.1016/j.bmcl.2008.04.019. (原始内容存档于2022-08-02) (英语).