2-氰基-3-(4-甲基苯基)丙烯酸甲酯
外观
2-氰基-3-(4-甲基苯基)丙烯酸甲酯 | |
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别名 | α-氰基-p-甲基肉桂酸甲酯 氰基(4-甲基亚苄基)乙酸甲酯 |
识别 | |
CAS号 | 65576-65-0 ![]() 13432-70-7(E) ![]() 151887-71-7(Z) ![]() |
性质 | |
化学式 | C12H11NO2 |
摩尔质量 | 201.22 g·mol−1 |
外观 | 白色固体(E)[1] |
熔点 | 92 °C(365 K)(E)[2] 92—93 °C(365—366 K)(E)[1] |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
2-氰基-3-(4-甲基苯基)丙烯酸甲酯是一种有机化合物,化学式为C12H11NO2。它可由氰乙酸甲酯和4-甲基苯甲醛的Knoevenagel缩合反应制得。[3]在金鸡纳碱衍生的硫脲催化下,它和过氧化叔丁醇在−20 °C反应,得到环氧化物(2-氰基-3-(4-甲基苯基)环氧丙酸甲酯)。[4]
参考文献
[编辑]- ^ 1.0 1.1 Hao Xu, Liyang Pan, Xiaomin Fang, Baoying Liu, Wenkai Zhang, Minghua Lu, Yuanqing Xu, Tao Ding, Haibo Chang. Knoevenagel condensation catalyzed by novel Nmm-based ionic liquids in water. Tetrahedron Letters. 2017-06, 58 (24): 2360–2365 [2023-02-21]. doi:10.1016/j.tetlet.2017.05.006. (原始内容存档于2022-10-23) (英语).. Supporting Information (doc) (页面存档备份,存于互联网档案馆)
- ^ Jamal Lasri, M. Adília Januário Charmier, Matti Haukka, Armando J. L. Pombeiro. Stereospecific Synthesis of Polysubstituted E -Olefins by Reaction of Acyclic Nitrones with Free and Platinum(II) Coordinated Organonitriles. The Journal of Organic Chemistry. 2007-02-01, 72 (3): 750–755 [2023-02-21]. ISSN 0022-3263. doi:10.1021/jo061659b. (原始内容存档于2023-02-21) (英语).
- ^ Stéphane Chalais, Pierre Laszlo, Arthur Mathy. Catalysis of the knoevenagel condensation. Tetrahedron Letters. 1985-01, 26 (37): 4453–4454 [2023-02-21]. doi:10.1016/S0040-4039(00)88928-5. (原始内容存档于2018-06-22) (英语).
- ^ Sara Meninno, Luca Zullo, Jacob Overgaard, Alessandra Lattanzi. Tunable Cinchona -Based Thioureas-Catalysed Asymmetric Epoxidation to Synthetically Important Glycidic Ester Derivatives. Advanced Synthesis & Catalysis. 2017-03-20, 359 (6): 913–918 [2023-02-21]. doi:10.1002/adsc.201700146. (原始内容存档于2023-02-21) (英语).