2,4,5-三羟基安非他命
外观
2,4,5-三羟基安非他命 | |
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IUPAC名 5-(2-Aminopropyl)benzene-1,2,4-triol | |
识别 | |
CAS号 | 136706-33-7 |
PubChem | 126234 |
ChemSpider | 112205 |
SMILES |
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性质 | |
化学式 | C9H13NO3 |
摩尔质量 | 183.2 g·mol−1 |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
2,4,5-三羟基安非他命(英語:2,4,5-Trihydroxyamphetamine,缩写THM,也称为α-甲基-6-羟基多巴胺,α-methyl-6-hydroxydopamine)是一种神經毒素和MDMA代谢产物,分子式C9H13NO3,由3,4-亚甲二氧基苯丙胺(MDA)开环羟基化生成,可降低色氨酸羟化酶[1]和酪氨酸羟化酶[2]的活性。
另见
[编辑]参考文献
[编辑]- ^ Elayan, I.; Gibb, J. W.; Hanson, G. R.; Lim, H. K.; Foltz, R. L.; Johnson, M. Short-term effects of 2,4,5-trihydroxyamphetamine, 2,4,5-trihydroxymethamphetamine and 3,4-dihydroxymethamphetamine on central tryptophan hydroxylase activity.. J Pharmacol Exp Ther. May 1993, 265 (2): 813–8. PMID 8496826.
- ^ Elayan I, Gibb JW, Hanson GR, Lim HK, Foltz RL, Johnson M. Short-term effects of 2,4,5-trihydroxyamphetamine, 2,4,5-trihydroxymethamphetamine and 3,4-dihydroxymethamphetamine on central tryptophan hydroxyls activity. J Pharmacol Exp Ther. 1993, 265 (2): 813–818. PMID 8496826.