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丹叶大黄素

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丹叶大黄素
Chemical structure of rhapontigenin
IUPAC名
5-[(E)-2-(3-Hydroxy-4-methoxyphenyl)ethen-1-yl]benzene-1,3-diol
别名 Protigenin
3,3',5-trihydroxy-4'-methoxystilbene
piceatannol 4'-methyl ether
识别
CAS号 500-65-2  checkY
PubChem 5320954
ChemSpider 4478875
SMILES
 
  • COc1ccc(cc1O)\C=C\c(cc2O)cc(O)c2
InChI
 
  • 1S/C15H14O4/c1-19-15-5-4-10(8-14(15)18)2-3-11-6-12(16)9-13(17)7-11/h2-9,16-18H,1H3/b3-2+
InChIKey PHMHDRYYFAYWEG-NSCUHMNNSA-N
性质
化学式 C15H14O4
摩尔质量 258.27 g/mol g·mol⁻¹
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

丹叶大黄素(英語:Rhapontigenin)是一种芪类有机化合物,分子式C15H14O4,存在于紫葛(学名:Vitis coignetiae)和闭苞买麻藤(学名:Gnetum cleistostachyum)中[1],能抑制人CYP1A1[2]

参考文献

[编辑]
  1. ^ Stilbenes from Gnetum cleistostachyum. Yao Chun-Suo, Lin Mao, LIiu Xin and Wang Ying-Hong, Huaxue xuebao, 2003, volume 61, no 8, pages 1331-1334, INIST法语Institut de l'information scientifique et technique:15332136
  2. ^ Chun, YJ; Ryu, SY; Jeong, TC; Kim, MY. Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin.. Drug metabolism and disposition: the biological fate of chemicals. 2001-04, 29 (4 Pt 1): 389–93. PMID 11259321.