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血绿素

维基百科,自由的百科全书
Chlorocruorin.

血绿素Chlorocruorin)是一种存在于多种环节动物(特别是多个多毛纲物种,例如龙介虫科血液血浆里的带氧蛋白[1][2][3],负责为身体组织携带氧气。这种血绿素与氧气结合的亲和力较大多数的血红蛋白为低,但与一氧化碳结合的亲和力,是人血内的血红素的570倍[4]

血绿素是一种(双色英语dichromatism)化合物,其颜色随含氧量而变:脱氧时呈绿色,但带氧时呈红色;在浓度低的溶液呈绿色、浓度高时变浅红色[5][6][7]

血绿素是一个巨大分子,但不存在于红血球内,而是自由地在血浆内漂浮[8][9]。其结构跟无脊椎动物血红蛋白英语erythrocruorin非常相像;而无脊椎动物血红蛋白的结构又跟肌红蛋白(myoglobin)只有几个subunits的差异。它本身由多组16-17kDa的类肌红蛋白单元排列,形成一个有超过一百个单元的巨型复杂构造,蛋白间有互连,总重量超过3600kDa。The only significant difference between chlorocruorin and erythrocruorin is that chlorocruorin carries an abnormal heme group structure[8]

参考文献

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  1. ^ H. Munro Fox. The Blood Circulation of Animals Possessing Chlorocruorin. Proceedings of the Royal Society B. 1933-04-01, 112 (779): 479–495. JSTOR 81599. doi:10.1098/rspb.1938.0042. 
  2. ^ R. F. Ewer, H. Munro Fox. On the Function of Chlorocruorin. Proceedings of the Royal Society B. 1940-08-09, 129 (855): 137–153. JSTOR 82389. doi:10.1098/rspb.1940.0033. 
  3. ^ D.W. Ewer. The blood systems of Sabella and Spirographis. Quarterly Journal of Microscopical Science. 1941, 82 (s2): 587–619 [2010-05-01]. (原始内容存档于2008-10-06). 
  4. ^ Cowles, David. Serpula vermicularis Linnaeus, 1767. Invertebrates of the Salish Sea. Rosario Beach Marine Laboratory at Walla Walla University. 2006 [2011-10-31]. (原始内容存档于2011-10-02). 
  5. ^ H. Munro Fox. Chlorocruorin: A Pigment Allied to Haemoglobin. Proceedings of the Royal Society B. 1926-02-01, 99 (696): 199–220. JSTOR 81088. doi:10.1098/rspb.1926.0008. 
  6. ^ H. Munro Fox. The Oxygen Affinity of Chlorocruorin. Proceedings of the Royal Society B. 1 September 1932, 111 (772): 356–363. JSTOR 81716. doi:10.1098/rspb.1932.0060. 
  7. ^ H. Munro Fox. On Chlorocruorin and Haemoglobin. Proceedings of the Royal Society B. 19 October 1949, 136 (884): 378–388. JSTOR 82565. doi:10.1098/rspb.1949.0031. 
  8. ^ 8.0 8.1 Pallavicini A, Negrisolo E, Barbato R; et al. The primary structure of globin and linker chains from the chlorocruorin of the polychaete Sabella spallanzanii. J. Biol. Chem. July 2001, 276 (28): 26384–90 [2016-03-17]. PMID 11294828. doi:10.1074/jbc.M006939200. (原始内容存档于2020-05-28). 
  9. ^ Lamy JN, Green BN, Toulmond A, Wall JS, Weber RE, Vinogradov SN. Giant Hexagonal Bilayer Hemoglobins. Chem Rev. 1996-12-19, 96 (8): 3113–3124. PMID 11848854. doi:10.1021/cr9600058 (英语). 

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