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1-氨甲基-5-甲氧基茚滿

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1-氨甲基-5-甲氧基茚滿
臨床資料
給藥途徑口服
ATC碼
  • 未分配
法律規範狀態
法律規範
  • 失控
識別資訊
  • (5-Methoxy-2,3-dihydro-1H-inden-1-yl)methanamine
CAS號1415750-28-5  checkY[EPA]
PubChem CID
ChemSpider
UNII
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C11H15NO
摩爾質量177.25 g·mol−1
3D模型(JSmol英語JSmol
  • NCC1CCc2c1ccc(OC)c2
  • InChI=1S/C11H15NO/c1-13-10-4-5-11-8(6-10)2-3-9(11)7-12/h4-6,9H,2-3,7,12H2,1H3 checkY
  • Key:WPBKCMLYKMDWRD-UHFFFAOYSA-N checkY

1-氨甲基-5-甲氧基茚滿英語1-Aminomethyl-5-methoxyindane,簡稱AMMI),是一種由普渡大學大衛·厄爾·尼科爾斯領導的團隊開發的藥物,它作為選擇性血清素釋放劑並與和DiFMDA具有相似親和力的血清素轉運蛋白結合。[1][2]

參見

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參考資料

[編輯]
  1. ^ Roman DL, Saldaña SN, Nichols DE, Carroll FI, Barker EL. Distinct molecular recognition of psychostimulants by human and Drosophila serotonin transporters. The Journal of Pharmacology and Experimental Therapeutics. February 2004, 308 (2): 679–87. PMID 14593087. S2CID 6439942. doi:10.1124/jpet.103.057836. 
  2. ^ Walline CC, Nichols DE, Carroll FI, Barker EL. Comparative molecular field analysis using selectivity fields reveals residues in the third transmembrane helix of the serotonin transporter associated with substrate and antagonist recognition. The Journal of Pharmacology and Experimental Therapeutics. June 2008, 325 (3): 791–800. PMC 2637348可免費查閱. PMID 18354055. doi:10.1124/jpet.108.136200.