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3-吡啶乙酸

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3-吡啶乙酸
識別
CAS號 501-81-5  checkY
性質
化學式 C7H7NO2
摩爾質量 137.14 g·mol−1
熔點 144—146 °C(417—419 K)[1]
相關物質
相關化學品 苯乙酸
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

3-吡啶乙酸是一種有機化合物,化學式為C7H7NO2,它是三種吡啶乙酸同分異構體之一。它可由3-溴甲基吡啶一氧化碳Pd(OH)2/C的催化下反應得到。[2]它和乙醇硫酸催化下反應,可以得到3-吡啶乙酸乙酯。[3]它在乙酸銅催化下、氧氣存在下脫羧,得到吡啶-3-甲醛[4]

參考文獻

[編輯]
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  2. ^ Wakuluk-Machado, Anne-Marie; Dewez, Damien F.; Baguia, Hajar; Imbratta, Miguel; Echeverria, Pierre-Georges; Evano, Gwilherm. Pd(OH)2/C, a Practical and Efficient Catalyst for the Carboxylation of Benzylic Bromides with Carbon Monoxide. Organic Process Research & Development (American Chemical Society (ACS)). 2019-12-19, 24 (5): 713–723. ISSN 1083-6160. doi:10.1021/acs.oprd.9b00402. 
  3. ^ Pranjal K. Baruah, Jason Dinsmore, Amber M. King, Christophe Salomé, Marc De Ryck, Rafal Kaminski, Laurent Provins, Harold Kohn. Synthesis, anticonvulsant activity, and neuropathic pain-attenuating activity of N-benzyl 2-amino-2-(hetero)aromatic acetamides. Bioorganic & Medicinal Chemistry. 2012-06, 20 (11): 3551–3564 [2022-01-14]. doi:10.1016/j.bmc.2012.04.002. (原始內容存檔於2018-06-30) (英語). 
  4. ^ Qiang Feng, Qiuling Song. Aldehydes and Ketones Formation: Copper-Catalyzed Aerobic Oxidative Decarboxylation of Phenylacetic Acids and α-Hydroxyphenylacetic Acids. The Journal of Organic Chemistry. 2014-02-21, 79 (4): 1867–1871 [2022-01-14]. ISSN 0022-3263. doi:10.1021/jo402778p. (原始內容存檔於2022-01-14) (英語).