D-蘇醛糖1-脫氫酶(英語:D-threo-aldose 1-dehydrogenase,EC 1.1.1.122(頁面存檔備份,存於網際網路檔案館)),是一種以NAD+或NADP+為受體、作用於供體CH-OH基團上的氧化還原酶。這種酶能催化以下酶促反應:
- D-蘇醛糖 + NAD+
D-蘇醛糖酸-1,5-內酯 + NADH + H+
D-蘇醛糖1-脫氫酶也能催化L-岩藻糖、D-阿拉伯糖、L-木糖等發生反應,石竹假單胞菌(Pseudomonas caryophylli)和動物的D-蘇醛糖1-脫氫酶和還分別表現出對L-葡萄糖和L-阿拉伯糖的活性,並可能受到對氯汞基苯甲酸、對羥基汞基苯甲酸、N-乙基順丁烯二酰亞胺等有機物質或Cu2+、Hg2+等陽離子的抑制。[1][2][3]
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- Schachter H, Sarney J, McGuire EJ, Roseman S. Isolation of diphosphopyridine nucleotide-dependent L-fucose dehydrogenase from pork liver. J. Biol. Chem. 1969, 244 (17): 4785–92. PMID 4309152.