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地特諾

維基百科,自由的百科全書
地特諾
臨床資料
商品名英語Drug nomenclatureBetaphrine
倍他福林
其他名稱Isopropylnorsynephrine, Isopropyloctopamine
識別資訊
  • 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenol
CAS號7376-66-1  checkY
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C11H17NO2
摩爾質量195.26 g·mol−1
3D模型(JSmol英語JSmol
  • CC(C)NCC(C1=CC=C(C=C1)O)O
  • InChI=1S/C11H17NO2/c1-8(2)12-7-11(14)9-3-5-10(13)6-4-9/h3-6,8,11-14H,7H2,1-2H3
  • Key:MPCPSVWSWKWJLO-UHFFFAOYSA-N

地特諾(英語:Deterenol ;亦稱 IsopropylnorsynephrineIsopropyloctopamine;商品名Betaphrine)是一種興奮劑,可作為β腎上腺素受體激動藥。其曾被用作膳食補充劑產品的成分,但由於可能導致心臟驟停而在大多數國家被禁用。[1][2][3][4][5]

參見

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參考文獻

[編輯]
  1. ^ Anderson WG. The sympathomimetic activity of N-isopropyloctopamine in vitro. The Journal of Pharmacology and Experimental Therapeutics. June 1983, 225 (3): 553–8. PMID 6306210. 
  2. ^ Mercader J, Wanecq E, Chen J, Carpéné C. Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium. Journal of Physiology and Biochemistry. September 2011, 67 (3): 443–52. PMID 21336650. S2CID 22449550. doi:10.1007/s13105-011-0078-2. 
  3. ^ Venhuis B, Keizers P, van Riel A, de Kaste D. A cocktail of synthetic stimulants found in a dietary supplement associated with serious adverse events. Drug Testing and Analysis. June 2014, 6 (6): 578–81. PMID 24802503. doi:10.1002/dta.1664. 
  4. ^ Zhao J, Wang M, Avula B, Khan IA. Detection and quantification of phenethylamines in sports dietary supplements by NMR approach. Journal of Pharmaceutical and Biomedical Analysis. March 2018, 151: 347–355. PMID 29413984. S2CID 46837518. doi:10.1016/j.jpba.2018.01.025可免費查閱. 
  5. ^ Cohen PA, Travis JC, Vanhee C, Ohana D, Venhuis BJ. Nine prohibited stimulants found in sports and weight loss supplements: deterenol, phenpromethamine (Vonedrine), oxilofrine, octodrine, beta-methylphenylethylamine (BMPEA), 1,3-dimethylamylamine (1,3-DMAA), 1,4-dimethylamylamine (1,4-DMAA), 1,3-dimethylbutylamine (1,3-DMBA) and higenamine. Clinical Toxicology. March 2021, 59 (11): 975–981. PMID 33755516. doi:10.1080/15563650.2021.1894333可免費查閱.