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PNU-91356A

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PNU-91356A
临床资料
ATC码
  • 未分配
识别信息
  • (10R)-10-(propylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
CAS号152886-85-6  checkY
PubChem CID
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C13H17N3O
摩尔质量231.30 g·mol−1
3D模型(JSmol英语JSmol
  • CCCNC1CC2=C3C(=CC=C2)NC(=O)N3C1
  • InChI=1S/C13H17N3O/c1-2-6-14-10-7-9-4-3-5-11-12(9)16(8-10)13(17)15-11/h3-5,10,14H,2,6-8H2,1H3,(H,15,17)/t10-/m1/s1
  • Key:XTWUNLMHXDDOMD-SNVBAGLBSA-N

PNU-91356A(也称为U-91356)是一种含氮有机化合物,分子式C13H17N3O,可作为多巴胺受体D2的选择性强效激动剂[1],对多巴胺受体D3D4和5-HT1A受体亲和力较低[2]

参考文献

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  1. ^ Moon MW, Morris JK, Heier RF, Hsi RS, Manis MO, Royer ME, et al. Medicinal chemistry of imidazoquinolinone dopamine receptor agonists. Drug Design and Discovery. 1993, 9 (3–4): 313–22. PMID 8104520. 
  2. ^ Piercey MF, Moon MW, Sethy VH, Schreur PJ, Smith MW, Tang AH, Von Voigtlander PF. Pharmacology of U-91356A, an agonist for the dopamine D2 receptor subtype. European Journal of Pharmacology. December 1996, 317 (1): 29–38. PMID 8982716. doi:10.1016/s0014-2999(96)00695-4. 

外部链接

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