曲喹辛
外观
(重定向自C24H27N3O3)
曲喹辛 | |
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IUPAC名 9,10-Dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-2,3,6,7-tetrahydro-4H-pyrimido[6,1-a]isoquinolin-4-one | |
识别 | |
CAS号 | 79855-88-2 ![]() |
PubChem | 5537 |
ChemSpider | 5336 |
SMILES |
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InChI |
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InChIKey | MCMSJVMUSBZUCN-UHFFFAOYSA-N |
性质 | |
化学式 | C24H27N3O3 |
摩尔质量 | 405.49 g·mol−1 |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
曲喹辛(英语:Trequinsin,也译为“曲林菌素”)是一种含氮有机化合物,分子式C24H27N3O3,可作为磷酸二酯酶抑制药[1],在体外实验(in vitro)中能增强精子活性[2]。
参考文献
[编辑]- ^ Whitaker, RM; Wills, LP; Stallons, LJ; Schnellmann, RG. CGMP-Selective Phosphodiesterase Inhibitors Stimulate Mitochondrial Biogenesis and Promote Recovery from Acute Kidney Injury. The Journal of Pharmacology and Experimental Therapeutics. 2013, 347 (3): 626–34. PMC 3836317
. PMID 24042162. doi:10.1124/jpet.113.208017.
- ^ McBrinn, RC; Fraser, J; Hope, AG; Gray, DW; Barratt, CLR; Martins da Silva, SJ; Brown, SG. Novel pharmacological actions of trequinsin hydrochloride improve human sperm cell motility and function.. British journal of pharmacology. 2019-12, 176 (23): 4521–4536. PMID 31368510. doi:10.1111/bph.14814.
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