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BHFF

维基百科,自由的百科全书
BHFF
识别信息
  • 5,7-Bis(1,1-dimethylethyl)-3-hydroxy-3(trifluoromethyl)-2(3H)-benzofuranone
CAS号123557-91-5  checkY
PubChem CID
ChemSpider
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.229.838 编辑维基数据链接
化学信息
化学式C17H21F3O3
摩尔质量330.35 g·mol−1
3D模型(JSmol英语JSmol
  • FC(F)(F)C2(O)c1cc(C(C)(C)C)cc(C(C)(C)C)c1OC2=O
  • InChI=1S/C17H21F3O3/c1-14(2,3)9-7-10(15(4,5)6)12-11(8-9)16(22,13(21)23-12)17(18,19)20/h7-8,22H,1-6H3 checkY
  • Key:RVNOANDLZIIFHB-UHFFFAOYSA-N checkY

BHFF,是一种有机化合物,GABAB受体的正向别构调节剂。在动物研究中展现了抗焦虑效应,有较好的口服生物学活性[1]

参考文献 

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  1. ^ Malherbe P, Masciadri R, Norcross RD, Knoflach F, Kratzeisen C, Zenner MT, et al. Characterization of (R,S)-5,7-di-tert-butyl-3-hydroxy-3-trifluoromethyl-3H-benzofuran-2-one as a positive allosteric modulator of GABAB receptors. British Journal of Pharmacology. June 2008, 154 (4): 797–811. PMC 2439845可免费查阅. PMID 18536733. doi:10.1038/bjp.2008.135. 

外部链接 

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