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2-异氰基丙烷

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2-异氰基丙烷
英文名 2-isocyanopropane
别名 异丙基异氰化物
识别
CAS号 598-45-8  checkY
SMILES
 
  • CC(C)[N+]#[C-]
性质
化学式 C4H7N
摩尔质量 69.11 g·mol−1
外观 无色恶臭液体[1]
沸点 85—87 °C(358—360 K)[2]
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

2-异氰基丙烷是一种有机化合物,化学式为C4H7N,它是异丁腈同分异构体。它可由异丙胺三氯甲烷氢氧化钠季铵盐的存在下在溶剂中反应得到[3]N-异丙基甲酰胺和三氯氧磷三乙胺的存在下于二氯甲烷中反应,也可得到2-异氰基丙烷。[1]它可作为配体和金属形成配合物[4]

参考文献

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  1. ^ 1.0 1.1 Lijie Wang, Jamie Ferguson, Fanlong Zeng. Palladium-catalyzed direct coupling of 2-vinylanilines and isocyanides: an efficient synthesis of 2-aminoquinolines. Organic & Biomolecular Chemistry. 2015, 13 (47): 11486–11491 [2021-04-07]. ISSN 1477-0520. doi:10.1039/C5OB01659B (英语). 
  2. ^ Henry Feuer, Harry Rubinstein, Arnold T. Nielsen. Reaction of Alkyl Isocyanides with Ozone. A New Isocyanate Synthesis 1. The Journal of Organic Chemistry. 1958-08, 23 (8): 1107–1109 [2021-04-07]. ISSN 0022-3263. doi:10.1021/jo01102a005 (英语). 
  3. ^ Debin Zeng, Yuying Ma, Rui Zhang, Quandeng Nie, Zhengjie Cui, Yaxin Wang, Luqing Shang, Zheng Yin. Synthesis and structure–activity relationship of α-keto amides as enterovirus 71 3C protease inhibitors. Bioorganic & Medicinal Chemistry Letters. 2016-04, 26 (7): 1762–1766 [2021-04-07]. doi:10.1016/j.bmcl.2016.02.039. (原始内容存档于2018-06-23) (英语). 
  4. ^ Belén Alvarez, M. Angeles Alvarez, M. Esther García, Daniel García-Vivó, Miguel A. Ruiz. C−C and C−N Couplings Following Hydride Addition on Isocyanide Cyclopolyenyl Dimolybdenum Complexes to Give Tethered Aldimine and Aminocarbene Derivatives. Chemistry - A European Journal. 2017-10-09, 23 (56): 14027–14038 [2021-04-07]. doi:10.1002/chem.201702998 (英语).