2-吡啶甲酸苯酯
外观
2-吡啶甲酸苯酯 | |
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别名 | 吡啶-2-甲酸苯酯 |
识别 | |
CAS号 | 26838-86-8 ![]() |
性质 | |
化学式 | C12H9NO2 |
摩尔质量 | 199.21 g·mol−1 |
外观 | 白色固体[1] |
熔点 | 72 °C[2] 78~79 °C[3] |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
2-吡啶甲酸苯酯是一种有机化合物,化学式为C12H9NO2。它可由2-吡啶甲酸和氯化亚砜反应,在真空浓缩后,在三乙胺的存在下再和苯酚在四氢呋喃中反应制得。[1]甲酸苯酯和2-溴吡啶在碱存在下、钯化合物催化下反应,也能得到烟酸苯酯。[2]它和2-萘硼酸在催化下反应,可以得到2-(2-萘基)吡啶。[4]
参考文献
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- ^ 2.0 2.1 Tsuyoshi Ueda, Hideyuki Konishi, and Kei Manabe. Palladium-Catalyzed Carbonylation of Aryl, Alkenyl, and Allyl Halides with Phenyl Formate. Org. Lett. 2012, 14, 12, 3100–3103. doi:10.1021/ol301192s.
- ^ Rivka R. R. Taylor and Robert A. Batey. A Hetero Diels–Alder Approach to the Synthesis of Chromans (3,4-Dihydrobenzopyrans) Using Oxonium Ion Chemistry: The Oxa-Povarov Reaction. J. Org. Chem. 2013, 78, 4, 1404–1420. doi:10.1021/jo302328s.
- ^ Kei Muto, Taito Hatakeyama, Kenichiro Itami, and Junichiro Yamaguchi. Palladium-Catalyzed Decarbonylative Cross-Coupling of Azinecarboxylates with Arylboronic Acids. Organic Letters (2016), 18(19), 5106-5109. doi:10.1021/acs.orglett.6b02556