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2-丁基咪唑

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2-丁基咪唑
英文名 2-butylimidazole
别名 2-正丁基咪唑
识别
CAS号 50790-93-7  checkY
PubChem 11815351
性质
化学式 C7H12N2
摩尔质量 124.18 g·mol−1
外观 晶体粉末[1]
密度 0.979±0.06 g·cm−3(20 °C)[2]
熔点 52 °C[1]
沸点 294 °C[1]
溶解性 2 g(25 °C)[2]
pKa 14.42±0.10(25 °C)[2]
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

2-丁基咪唑是一种有机化合物,化学式为C7H12N2。它可由1-(二乙氧基甲基)咪唑的锂盐和1-碘丁烷反应得到,产物分别用盐酸、碳酸氢钠处理后用三氯甲烷萃取提纯。[3]2-丁基-4,5-二氢咪唑的氧化反应也能得到2-丁基咪唑。[4]它和碳酸钠的存在下于二氧六环中反应,可以得到2-丁基-4,5-二碘咪唑。[5]它可以和形成金属有机框架材料[6]

参考文献

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  1. ^ 1.0 1.1 1.2 2-Butylimidazole 97.0+%, TCI America(TM). fisher scientific. [2021-09-15]. (原始内容存档于2021-09-15). 
  2. ^ 2.0 2.1 2.2 Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 ((C) 1994-2021 ACD/Labs). Retrieved from SciFinder. [2021-09-15].
  3. ^ N. J. Curtis, R. S. Brown. An easily introduced and removed protecting group for imidazole nitrogen: a convenient route to 2-substituted imidazoles. The Journal of Organic Chemistry. 1980-09, 45 (20): 4038–4040 [2021-09-15]. ISSN 0022-3263. doi:10.1021/jo01308a019. (原始内容存档于2021-09-15) (英语). 
  4. ^ Mohammad Abdollahi-Alibeik, Iraj Mohammadpoor-Baltork, Mohammad Ali Zolfigol. Alumina supported potassium permanganate: an efficient reagent for chemoselective dehydrogenation of 2-imidazolines under mild conditions. Bioorganic & Medicinal Chemistry Letters. 2004-12, 14 (24): 6079–6082 [2021-09-15]. doi:10.1016/j.bmcl.2004.09.070 (英语). 
  5. ^ Steven J. Wittenberger, Andrew Tasker, Bryan K. Sorensen, B. Gregory Donner. 2-Butyl-4-iodoimidazole-5-carboxaldehyde: A Versatile Intermediate for the Synthesis of Highly Functionalized Imidazoles. Synthetic Communications. 1993-12, 23 (22): 3231–3248 [2021-09-15]. ISSN 0039-7911. doi:10.1080/00397919308011184 (英语). 
  6. ^ Hatem M. Titi, Mihails Arhangelskis, Athanassios D. Katsenis, Cristina Mottillo, Ghada Ayoub, Jean-Louis Do, Athena M. Fidelli, Robin D. Rogers, Tomislav Friščić. Metal–Organic Frameworks as Fuels for Advanced Applications: Evaluating and Modifying the Combustion Energy of Popular MOFs. Chemistry of Materials. 2019-07-09, 31 (13): 4882–4888 [2021-09-15]. ISSN 0897-4756. doi:10.1021/acs.chemmater.9b01488. (原始内容存档于2022-01-06) (英语).