酮泛解酸
外观
酮泛解酸 | |
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别名 | 4-Hydroxy-3,3-dimethyl-2-oxobutanoic acid; 2-Dehydropantoic acid |
识别 | |
CAS号 | 470-30-4 |
PubChem | 38 |
ChemSpider | 37 |
SMILES |
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Beilstein | 2242422 |
ChEBI | 17094 |
DrugBank | DB03795 |
KEGG | C00966 |
性质 | |
化学式 | C6H10O4 |
摩尔质量 | 146.14 g·mol−1 |
外观 | colorless or white |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
酮泛解酸(英语:Ketopantoic acid)是一种有机化合物,结构简式HOCH2(CH3)2CC(O)CO2H,结构上与泛解酸类似,属于Ω-羟基酮酸,在体内由α-酮异戊酸羟甲基化生成,在生理条件下以共轭碱的形式存在[1][2]。
参考文献
[编辑]- ^ Matak-Vinković, Dijana; Vinković, Mladen; Saldanha, S. Adrian; Ashurst, Jennifer L.; von Delft, Frank; Inoue, Tsuyoshi; Miguel, Ricardo Nunez; Smith, Alison G.; Blundell, Tom L.; Abell, Chris. Crystal Structure of Escherichia coli Ketopantoate Reductase at 1.7 Å Resolution and Insight into the Enzyme Mechanism. Biochemistry. 2001, 40 (48): 14493–14500. PMID 11724562. doi:10.1021/bi011020w.
- ^ Begley, Tadhg P.; Kinsland, Cynthia; Strauss, Erick. The Biosynthesis of Coenzyme a in Bacteria. Cofactor Biosynthesis. Vitamins & Hormones 61. 2001: 157–171. ISBN 9780127098616. PMID 11153265. doi:10.1016/S0083-6729(01)61005-7.