过氧化麦角固醇
外观
过氧化麦角固醇 | |
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IUPAC名 (3S,5S,8S,9R,10R,13R,14R,17R)-10,13-dimethyl-17-[(1R,2E,4R)-1,4,5-trimethylhex-2-en-1-yl]-1,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-2H-5,8-epidioxycyclopenta[a]phenanthren-3-ol | |
识别 | |
CAS号 | 2061-64-5 ![]() |
PubChem | 5351516 |
ChemSpider | 4508532 |
SMILES |
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InChI |
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ChEBI | 65858 |
性质 | |
化学式 | C28H44O3 |
摩尔质量 | 428.647 g·mol⁻¹ |
密度 | 1.08g/cm3 |
沸点 | 499.7 °C(773 K) |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
过氧化麦角固醇(英语:Ergosterol peroxide,也称作5α,8α-二氧桥-22E-麦角甾-6,22-二烯-3β-醇,5α,8α-epidioxy-22E-ergosta-6,22-dien-3β-ol),分子式C28H44O3,是一种甾体衍生物,存在于真菌、酵母、地衣、海绵中[1][2][3][4][5],具有免疫抑制[6]、抗炎[7]等活性。
参考文献
[编辑]- ^ Lobo AM, Abreu PM, Prabhakar S, Godhino LS, Jones R, Rzepa HS, Williams DJ. Triterpenoids of the fungus Pisolithus tinctorius. Phytochemistry. 1988, 27 (11): 3569–74. doi:10.1016/0031-9422(88)80770-2.
- ^ Jimenez C, Quinoa E, Rignera R, Vilalta R, Quintella JM. The dietary origin of epidioxy steroids in Actinia equina. A carbon14 incorporation experiment. Journal of Natural Products. 1989, 52 (3): 619–22. doi:10.1021/np50063a023.
- ^ Kahols K, Kangas L, Hiltunen R. Ergosterol peroxide, an active compound from Inonotus radiatus. Planta Medica. 1989, 55 (4): 389–90. PMID 2813575. doi:10.1055/s-2006-962036.
- ^ Tchouankeu JC, Nyasse B, Tsamo E, Sondengam B, Morin C. An ergostane derivative from the bark of Entandrophragma utile. Phytochemistry. 1992, 31 (2): 704–705. doi:10.1016/0031-9422(92)90067-Z.
- ^ Fujimoto H, Nakayama Y, Yamazaki M. Isolation and characterization of immunosuppressive components of three mushrooms, Pisolithus tinctorius, Microporus flabelliformis and Lenzites betulina. Chem. Pharm. Bull. 1994, 42 (3): 694–97. PMID 8004718. doi:10.1248/cpb.42.694
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- ^ Yasukawa K, Akihisa T, Kanno H, Kaminaga T, Izumida M, Sakoh T, Tamura T, Takido M. Inhibitory effects of sterols isolated from Chlorella vulgaris on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and tumor promotion in mouse skin. Biological and Pharmaceutical Bulletin. 1996, 19 (4): 573–576. PMID 8860961. doi:10.1248/bpb.19.573
.
- ^ Lindequist U, Lesnau A, Teuscher E, Pilgrim H. Antiviral activity of ergosterol peroxide. Pharmazie. 1989, 44 (8): 579–80. PMID 2594833.