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诺孕烯酮

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诺孕烯酮
临床资料
商品名英语Drug nomenclatureOgyline, Planor, Miniplanor
其他名称RU-2010; A-301; 17α-Ethynyltrienolone; 17α-Ethynyltrenbolone; Δ9,11-Norethisterone; 17α-Ethynylestra-4,9,11-trien-17β-ol-3-one
给药途径口服给药
药物类别英语Drug classProgestogen; Progestin; Androgen; Anabolic steroid
ATC码
识别信息
  • (8S,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
CAS号848-21-5  checkY
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.011.544 编辑维基数据链接
化学信息
化学式C20H22O2
摩尔质量294.39 g·mol−1
3D模型(JSmol英语JSmol
  • O=C4\C=C3/C(=C2/C=C\[C@]1([C@@H](CC[C@]1(C#C)O)[C@@H]2CC3)C)CC4
  • InChI=1S/C20H22O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,8,10,12,17-18,22H,4-7,9,11H2,2H3/t17-,18+,19+,20+/m1/s1 checkY
  • Key:GVDMJXQHPUYPHP-FYQPLNBISA-N checkY

诺孕烯酮(英语:Norgestrienone,或译为去甲孕三烯酮商品名: Ogyline, Planor, Miniplanor 等)是一种甾体药物,分子式C20H22O2,由法国药企Roussel Uclaf开发,可用作复合口服避孕药,常与炔雌醇联用[1][2][3][4][5]

参考文献

[编辑]
  1. ^ Elks J. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 887–. ISBN 978-1-4757-2085-3. 
  2. ^ Morton IK, Hall JM. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 6 December 2012: 202– [2023-02-02]. ISBN 978-94-011-4439-1. (原始内容存档于2023-01-10). 
  3. ^ Diaz S, Pavez M, Quinteros E, Diaz J, Robertson DN, Croxatto HB. Clinical trial with subdermal implants containing norgestrienone. Contraception. October 1978, 18 (4): 429–40. PMID 720075. doi:10.1016/0010-7824(78)90027-6. 
  4. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000: 751–. ISBN 978-3-88763-075-1. 
  5. ^ Sweetman, Sean C. (编). Sex hormones and their modulators. Martindale: The Complete Drug Reference 36th. London: Pharmaceutical Press. 2009: 2122 [2023-02-02]. ISBN 978-0-85369-840-1. (原始内容存档于2020-05-29). Norgestrienone is a progestogen structurally related to norethisterone that has been used as an oral contraceptive. Typical doses have been 2 mg daily with an oestrogen, and 350 micrograms daily when used alone.