苯甲酰丙酮
外观
苯甲酰丙酮 | |
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IUPAC名 1-phenylbutane-1,3-dione | |
别名 | 1-苯基-1,3-丁二酮 |
识别 | |
CAS号 | 93-91-4 |
PubChem | 7166 |
ChemSpider | 6898 |
SMILES |
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性质 | |
化学式 | C10H10O2 |
摩尔质量 | 162.19 g·mol−1 |
密度 | 1.0599 g/cm3 |
熔点 | 56 °C(329 K) |
沸点 | 261.5 °C(535 K) |
危险性 | |
GHS危险性符号![]() | |
GHS提示词 | 警告 |
H-术语 | H315, H319, H335 |
P-术语 | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405 |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
苯甲酰丙酮是一种有机化合物,化学式为C6H5C(O)CH2C(O)CH3。它是一种β-二羰基化合物,为许多杂环化合物(如吡唑)的前体。[1]苯甲酰丙酮主要以烯醇(C6H5C(OH)=CHC(O)CH3)的形式存在。[2]它的共轭碱(pKa = 8.7)可以和过渡金属或镧系金属形成稳定的配合物。[3]
参考文献
[编辑]- ^ Penning, Thomas D.; Talley, John J.; Bertenshaw, Stephen R.; Carter, Jeffery S.; Collins, Paul W.; Docter, Stephen; Graneto, Matthew J.; Lee, Len F.; Malecha, James W.; Miyashiro, Julie M.; Rogers, Roland S.; Rogier, D. J.; Yu, Stella S.; Anderson, Gary D.; Burton, Earl G.; Cogburn, J. Nita; Gregory, Susan A.; Koboldt, Carol M.; Perkins, William E.; Seibert, Karen; Veenhuizen, Amy W.; Zhang, Yan Y.; Isakson, Peter C. Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3- (Trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib). Journal of Medicinal Chemistry. 1997, 40 (9): 1347–1365. PMID 9135032. doi:10.1021/JM960803Q.
- ^ Jones, R. D. G. The crystal and molecular structure of the enol form of 1-phenyl-1,3-butanedione (Benzoylacetone) by neutron diffraction. Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 1976, 32 (7): 2133–2136. doi:10.1107/S0567740876007267.
- ^ McGehee, M. D.; Bergstedt, T.; Zhang, C.; Saab, A. P.; o'Regan, M. B.; Bazan, G. C.; Srdanov, V. I.; Heeger, A. J. Narrow Bandwidth Luminescence from Blends with Energy Transfer from Semiconducting Conjugated Polymers to Europium Complexes. Advanced Materials. 1999, 11 (16): 1349–1354. doi:10.1002/(SICI)1521-4095(199911)11:16<1349::AID-ADMA1349>3.0.CO;2-W.