甲酰乙酸
外观
甲酰乙酸 | |
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别名 | 3-氧代丙酸 缩苹果酸半醛 |
识别 | |
CAS号 | 926-61-4 ![]() |
SMILES |
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性质 | |
化学式 | C3H4O3 |
摩尔质量 | 88.06 g·mol−1 |
相关物质 | |
相关化学品 | 乙酰乙酸 |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
甲酰乙酸是一种有机化合物,化学式为C3H4O3。它可由苹果酸、高碘酸和N-溴代烟酰胺在乙酸汞催化下反应制得[1],或由α-当归内酯经高碘酸钠/四氧化锇氧化得到。[2]
在一种铱的配合物的催化下,它可以和甲酸铵反应,生成甘氨酸[3]。琥珀酸半醛脱氢酶(YNEI)可以使甲酰乙酸转化为丙二酸。[4]
参考文献
[编辑]- ^ Pushpalatha, L. Kinetics and mechanism of oxidation of malic acid by N-bromonicotinamide. International Journal of Chemistry (Mumbai, India), 2012. 1 (2): 199-204. ISSN 2249-2119.
- ^ Traverso, G.; Pirillo, D.; Strazzolini, P. On the coupled sodium periodate/osmium tetroxide oxidation of some unsaturated γ-lactones. Farmaco, Edizione Scientifica, 1979. 34 (12): 1071-1072. ISSN 0430-0920.
- ^ Nguyen, Dat P.; Sladek, Rudolph N.; Do, Loi H. Scope and limitations of reductive amination catalyzed by half-sandwich iridium complexes under mild reaction conditions. Tetrahedron Letters. 2020-08, 61 (32): 152196. doi:10.1016/j.tetlet.2020.152196.
- ^ Song, Chan Woo; Kim, Je Woong; Cho, In Jin; Lee, Sang Yup. Metabolic Engineering of Escherichia coli for the Production of 3-Hydroxypropionic Acid and Malonic Acid through β-Alanine Route. ACS Synthetic Biology (American Chemical Society (ACS)). 2016-03-14, 5 (11): 1256–1263. ISSN 2161-5063. doi:10.1021/acssynbio.6b00007.