甘草次酸
外观
(重定向自C30H46O4)
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临床资料 | |
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商品名 | Arthrodont, PruClair |
AHFS/Drugs.com | 国际药品名称 |
给药途径 | Oral, topical |
ATC码 | |
法律规范状态 | |
法律规范 | |
识别信息 | |
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CAS号 | 471-53-4 |
PubChem CID | |
ChemSpider | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.006.769 |
化学信息 | |
化学式 | C30H46O4 |
摩尔质量 | 470.6838 |
3D模型(JSmol) | |
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甘草次酸(glycyrrhetinic acid,或glycyrrhetic acid,也叫Enoxolone)是一种五环三萜物质,由草药光果甘草的甘草酸水解得到故而得名。甘草次酸可以看作是β-香树脂醇(齐墩果烷型)的衍生物,从而作为甘草酸的糖苷配基。甘草次酸常作为香料使用,也用来掩盖芦荟和奎宁等药物的苦味。[1][2][3][4][5]
另见
[编辑]参考文献
[编辑]- ^ Chandler, RF. Liquorice, more than just a flavour. Canadian Pharmaceutical Journal. 1985, (118): 420–4.
- ^ Badam, L.; Amagaya, S.; Pollard, B. In vitro activity of licorice and glycyrrhetinic acid on Japanese encephalitis virus.. J. Community Dis. 1997, 29: 91–99.
- ^ Fuji, H.Y.; Tian, J.; Luka, C. Effect of glycyrrhetinic acid on influenza virus and pathogenic bacteria.. Bull. Chin. Mater. Med. 1986, 11: 238–241.
- ^ Guo, N.; Takechi, M.; Uno, C. Protective effect of glycyrrhizine in mice with systemic Candida albicans infection and its mechanism. J. Pharm. Pharmacol. 1991, 13 (5): 380–383. PMID 1839259.
- ^ Salari, M. H.; Sohrabi, N.; Kadkhoda, Z.; and Khalili, M. B.; capnophilic bacteria isolated from specimens of periodontitis patients. Antibacterial effects of Enoxolone on periodontopathogenic. Iran. Biomed. J. 2003, 7: 39–42.
延伸阅读
[编辑]- Saponin Glycosides (页面存档备份,存于互联网档案馆), by Georges-Louis Friedli, URL accessed Sept 2010.
外部链接
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