CTLA-4
外观
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(重定向自细胞毒性T淋巴细胞相关抗原4)
CTLA4又称CTLA-4(细胞毒性T淋巴细胞相关抗原4,cytotoxic T-lymphocyte-associated protein 4)或CD152(分化群152),是一种蛋白质受体[7]。CTLA-4蛋白由小鼠的Ctla4[8]和人类的CTLA4基因编码[9]。CTLA-4于1991年首次被发现[10]。
参考文献
[编辑]- ^ 與細胞毒性T淋巴細胞相關抗原4相關的疾病;在維基數據上查看/編輯參考.
- ^ 對細胞毒性T淋巴細胞相關抗原4起作用的藥物;在維基數據上查看/編輯參考.
- ^ 3.0 3.1 3.2 GRCh38: Ensembl release 89: ENSG00000163599 - Ensembl, May 2017
- ^ 4.0 4.1 4.2 GRCm38: Ensembl release 89: ENSMUSG00000026011 - Ensembl, May 2017
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ De-novo and acquired resistance to immune checkpoint targeting. The Lancet. Oncology. December 2017, 18 (12): e731–e741. PMID 29208439. doi:10.1016/s1470-2045(17)30607-1.
- ^ A new member of the immunoglobulin superfamily--CTLA-4. Nature. 1987, 328 (6127): 267–70. Bibcode:1987Natur.328..267B. PMID 3496540. doi:10.1038/328267a0.
- ^ Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains. European Journal of Immunology. December 1988, 18 (12): 1901–5. PMID 3220103. doi:10.1002/eji.1830181206.
- ^ Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science. November 1995, 270 (5238): 985–8. Bibcode:1995Sci...270..985W. JSTOR 2888113. PMID 7481803. doi:10.1126/science.270.5238.985.